Log In|Sign Up
中文小鼠
Lgmn - legumain
Alias:
AEP
Prsc1
Favorite
这个基因编码半胱氨酸肽酶家族C13的一个成员，在内质网/溶酶体降解系统中扮演重要角色。编码的无活性前原蛋白经历自催化去除C端抑制性前肽，生成活性内肽酶，切割天冬氨酸残基C端的蛋白质底物。缺乏编码蛋白的小鼠在蛋白质溶酶体加工中表现出缺陷，导致其在溶酶体中积累，并表现出类似于噬血细胞性淋巴组织细胞病的症状。[RefSeq，2016年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Lgmn Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
