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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Eif2ak2 - eukaryotic translation initiation factor 2-alpha kinase 2
Alias:
Pkr
Tik
Prkr
2310047A08Rik
4732414G15Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这种基因具有双链RNA结合活性和蛋白激酶活性。参与多个过程,包括负调控病毒基因组复制;正调控细胞内信号传导;以及调控造血干细胞分化。在细胞蛋白代谢过程、内质网未折叠蛋白响应和凋亡过程的负调控中具有上游作用或位于细胞内。预测位于细胞核和细胞质核周区域。预测在细胞质中活性。在几个结构中表达,包括生殖系统、心脏、肝脏、肺和脾脏。这种基因的人类同源物与阿尔茨海默病、亨廷顿病、帕金森病和乙型肝炎有关。与人类EIF2AK2(真核翻译起始因子2α激酶2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:19106
ENSEMBL:ENSMUSG00000024079
UNIPROT:Q03963
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
19106
2
16
32069 bp
58.28
11
25
Eif2ak2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Name
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IF
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