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中文小鼠
Ppargc1a - peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Alias:
Pgc1
PGC-1
Pgco1
Gm11133
Ppargc1
Pgc-1alpha
A830037N07Rik
PPARGC-1-alpha
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这个基因编码一个转录协同激活因子，诱导并协调基因表达，调节线粒体生物发生、呼吸、肝糖异生、棕色脂肪和肌肉纤维类型转换中的生热程序。缺乏编码蛋白的小鼠表现出降低的生热能力、过度活跃和对饮食诱导的肥胖的抵抗力。在心脏中特定缺乏编码蛋白的小鼠表现出围产期心肌病。可变剪接导致多个转录子变异体。[由RefSeq，2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Ppargc1a Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
