Pnmt - phenylethanolamine-N-methyltransferase

Predicted to enable phenylethanolamine N-methyltransferase activity. Predicted to be involved in epinephrine biosynthetic process and norepinephrine metabolic process. Predicted to act upstream of or within catecholamine biosynthetic process and methylation. Predicted to be located in several cellular components, including axon; dendrite; and perikaryon. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; brain; gonad; and metanephros. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; and multiple sclerosis. Orthologous to human PNMT (phenylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]