Log In|Sign Up
中文小鼠
Pms2 - PMS1 homolog2, mismatch repair system component
Alias:
Pmsl2
Favorite
具有预测的ATP水解活性，并能与单碱基插入或删除结合。预测能对MutSalpha复合物结合活性和单链DNA结合活性做出贡献。参与IgA同型转换的正调控；IgG同型转换的正调控；以及免疫球蛋白基因的体细胞超突变。在错配修复和免疫球蛋白基因段的体细胞重组的上游或内部发挥作用。是MutLalpha复合物的一部分。在小脑；生殖系统；视网膜；和尿道上皮中表达。该基因的人类同源物与林奇综合症；遗传性非息肉状结肠癌4型；错配修复癌症综合症；卵巢癌；和膀胱癌有关。与人类PMS2（PMS1同系2，错配修复系统成分）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Pms2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
