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Pml - promyelocytic leukemia

Alias:
Trim19
1200009E24Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活SMAD结合活性。参与几个过程,包括对其他生物体的防御反应;基因表达的调控;以及p53类介体的信号传导。在几个过程的上游或内部发挥作用,包括凋亡信号通路;宏分子代谢过程的正向调节;和跨膜受体蛋白丝氨酸/苏氨酸激酶信号通路。位于PML体;胞质;和核基质中。是内质网膜的外部组件。与异质染色质共定位。在几个结构中表达,包括消化系统;大脑;早期概念期;生殖泌尿系统;和血淋巴样系统腺体。该基因的人类同源物涉及急性早幼粒细胞白血病和皮肤癌。与人PML(PML核体支架)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
9
9
32616 bp
98.24
9
39

Pml Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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