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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Plat - plasminogen activator, tissue
Alias:
tPA
D8Ertd2e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码纤维溶解途径的关键酶。编码的蛋白质被纤溶酶蛋白水解处理,生成异源二聚丝氨酸蛋白酶,切割前酶纤溶酶原,产生纤溶酶,这是一种分解纤维蛋白凝块所需的蛋白酶。此外,编码的蛋白质涉及其他生物过程,如突触可塑性、细胞迁移和组织重塑。缺乏编码蛋白质的小鼠显示海马中长时程增强的减少,相反,过表达编码蛋白质的转基因小鼠长时程增强的增强和延长。[RefSeq,2015年7月提供]
Related ID:
NCBI:18791
ENSEMBL:ENSMUSG00000031538
UNIPROT:P11214
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
18791
3
14
25210 bp
63.10
7
4
Plat Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
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Interactions
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Acting
Regulation
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Type
Name
MGI
Strain of Origin
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References Literature
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Year
IF
No Data Found!
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