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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
E4F1 - E4F Transcription Factor 1
Alias:
E4F
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的锌指蛋白是几种细胞转录因子中的一种,其DNA结合活性通过腺病毒E1A的作用进行调节。全长蛋白质通过蛋白水解切割生成一个50kDa的氨基端产物。该蛋白质受到E1A诱导的磷酸化的差异调节。全长基因产物在缺乏E1A的情况下抑制E4启动子的转录,而50kDa的形式在其存在下作为转录激活子发挥作用。可变剪接产生多种编码不同蛋白质的转录本。[RefSeq,2014年1月提供]
Related ID:
NCBI:1877
ENSEMBL:ENSG00000167967
HGNC:3121
UNIPROT:Q66K89
OMIM:603022
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1877
12
14
12152 bp
83.50
38
--
5
26
E4F1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
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Mutations
No data available
Transcripts & Proteins
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
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Status
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Link
No data available
References Literature
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No Data Found!
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