人类

E4F1 - E4F Transcription Factor 1

Alias:
E4F
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的锌指蛋白是几种细胞转录因子中的一种,其DNA结合活性通过腺病毒E1A的作用进行调节。全长蛋白质通过蛋白水解切割生成一个50kDa的氨基端产物。该蛋白质受到E1A诱导的磷酸化的差异调节。全长基因产物在缺乏E1A的情况下抑制E4启动子的转录,而50kDa的形式在其存在下作为转录激活子发挥作用。可变剪接产生多种编码不同蛋白质的转录本。[RefSeq,2014年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
12
14
12152 bp
83.50
38
--
5
26

E4F1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top