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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Prkci - protein kinase C, iota
Alias:
Pkci
Pkcl
Prkcl
PKClambda
mKIAA4165
aPKClambda
2310021H13Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活蛋白激酶C活性。参与几个过程,包括细胞对胰岛素刺激的响应;正调控葡萄糖导入;以及正调控蛋白质定位到质膜。在肌动蛋白丝组织、顶/基底细胞极性建立和眼光感受器细胞发育的上游或内部发挥作用。位于几个细胞组件中,包括Schmidt-Lanterman切迹、顶质膜和细胞核。在几个结构中表达,包括消化系统、大脑、生殖泌尿系统、肺和感觉器官。用于研究腹部肥胖-代谢综合症、肥胖和2型糖尿病。与人类的PRKCI(蛋白激酶C iota)正同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:18759
ENSEMBL:ENSMUSG00000037643
UNIPROT:Q62074
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
18759
2
18
56997 bp
68.20
15
15
Prkci Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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