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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Prkaca - protein kinase, cAMP dependent, catalytic, alpha
Alias:
PKCD
Pkaca
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码丝氨酸/苏氨酸蛋白激酶家族的一员。全酶,即蛋白激酶A(也称为环-AMP依赖性蛋白激酶),调节细胞对环-AMP水平变化的反应。这个基因编码蛋白激酶A的α催化亚基。蛋白激酶A介导的信号传导是通过磷酸化靶蛋白来传递的,对于许多细胞功能,包括哺乳动物精子成熟和活力,都是非常重要的。选择性剪接产生了多种转录变异体。这个基因的一个假基因已经在X染色体上定义。[由RefSeq,2013年4月提供]
Related ID:
NCBI:18747
ENSEMBL:ENSMUSG00000005469
UNIPROT:P05132
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
18747
2
10
23467 bp
40.57
6
27
Prkaca Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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