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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pitx1 - paired-like homeodomain transcription factor 1
Alias:
Bft
Potx
Ptx1
P-OTX
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性结合RNA聚合酶II,并特异性结合RNA聚合酶II的顺式调控区域序列。参与胚胎后肢形态发生;负调控DNA模板的转录;以及正调控RNA聚合酶II的转录。在动物器官发育的上游或内部发挥作用;后肢形态发生;和成肌细胞命运承诺。位于细胞质和细胞核中。是转录调节复合物的一部分。在包括消化系统;大脑;胚胎间充质;生殖泌尿系统;和感觉器官在内的几个结构中表达。用于研究先天性足畸形。此基因的人类同源物与先天性足畸形有关。与人类PITX1(同源域1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:18740
ENSEMBL:ENSMUSG00000021506
UNIPROT:P70314
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
18740
3
3
11146 bp
34.08
7
11
Pitx1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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