Log In|Sign Up
中文人类
E2F3 - E2F Transcription Factor 3
Alias:
E2F-3
Favorite
这个基因编码一个小家族转录因子成员，该成员通过结合DP相互作用伴侣蛋白来发挥作用。编码的蛋白质能识别DNA中的特定序列基序，并直接与视网膜母细胞瘤蛋白(pRB)相互作用，以调控参与细胞周期的基因表达。这个基因的拷贝数和活性改变已经在许多人类癌症中观察到。这个基因在染色体2和17上存在假基因。选择性剪接产生了多种转录变异体。[RefSeq,2013年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
E2F3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
