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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pdx1 - pancreatic and duodenal homeobox 1
Alias:
Ipf1
IDX-1
IPF-1
Mody4
STF-1
pdx-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录因子活性;RNA聚合酶II顺式调控区域序列特异性DNA结合活性;以及染色质结合活性。在几个过程的上游或内部发挥作用,包括细胞凋亡过程的负调控;胰腺发育;以及RNA聚合酶II的转录调控。位于核斑点中。在几个结构中表达,包括肠道;肝脏和胆道系统;生殖系统;感觉器官;以及骨架。用于研究青少年发病型糖尿病;青少年发病型糖尿病4型;以及1型糖尿病。该基因的人类同源物涉及脑梗死;高血糖;青少年发病型糖尿病4型;胰腺发育不全;以及2型糖尿病。与人类PDX1(胰腺和十二指肠同源盒1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:18609
ENSEMBL:ENSMUSG00000029644
UNIPROT:P52946
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
18609
1
2
5752 bp
31.00
21
9
Pdx1 Genetics information (+)
GRCm39
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* This data comes from NCBI.
Gene Expression
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