小鼠

Pdgfra - platelet derived growth factor receptor, alpha polypeptide

Alias:
CD140a
Pdgfr-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种受体酪氨酸激酶家族的蛋白质成员。血小板来源的生长因子蛋白质配体结合到这个受体上会触发受体的二聚化和自磷酸化,从而导致几个下游信号通路被激活。通过编码的受体的信号传导在胃胚形成和几乎所有器官系统的发育中发挥作用。据报道,缺乏这个基因功能拷贝的小鼠在肺、骨骼、睾丸和中枢神经系统方面表现出缺陷,并在出生后不久死亡。基因转录本的替代剪接和内含子多腺苷化与成年小鼠的肌肉再生和纤维化有关。[由RefSeq,2017年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
7
23
46880 bp
122.68
33
13

Pdgfra Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
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Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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