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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pde4b - phosphodiesterase 4B, cAMP specific
Alias:
Dpde4
dunce
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
3',5'-环-AMP磷酸二酯酶活性; γ-微管蛋白结合活性; 和跨膜转运蛋白结合活性。参与几个过程,包括细胞对肾上腺素刺激的响应; 负调节腺苷酸环化酶激活的肾上腺素受体信号通路,涉及心脏过程; 和肌肉系统过程的调节。在几个过程的上游或内部发挥作用,包括细胞对脂质多糖的响应; 中性粒细胞的趋化作用; 和中性粒细胞稳态。位于几个细胞组件中,包括Z带; 中心体; 和突触囊泡。是γ-微管蛋白复合物和电压门控钙通道复合物的一部分。在几个结构中表达,包括消化系统; 耳; 生殖泌尿系统; 神经系统; 和呼吸系统。与人类的PDE4B(磷酸二酯酶4B)正同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:18578
ENSEMBL:ENSMUSG00000028525
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
18578
17
16
519931 bp
Unknown
7
11
Pde4b Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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