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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DVL2 - Dishevelled Segment Polarity Protein 2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个dishevelled(dsh)蛋白家族的成员。脊椎动物的dsh蛋白与果蝇dsh蛋白的氨基酸序列相似性约为40%。这个基因编码一个90kD的蛋白,该蛋白在翻译后发生磷酸化,形成95kD的细胞质蛋白,可能参与由多种Wnt蛋白介导的信号传导途径。dishevelled在Wnt信号传导中的功能机制可能在多细胞生物中保守。[由RefSeq,2008年7月提供]
Related ID:
NCBI:1856
ENSEMBL:ENSG00000004975
HGNC:3086
UNIPROT:O14641
OMIM:602151
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1856
6
15
9176 bp
78.95
38
--
4
17
DVL2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Name
MGI
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Status
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References Literature
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