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中文小鼠
Pcsk5 - proprotein convertase subtilisin/kexin type 5
Alias:
PC5
PC6
SPC6
b2b585Clo
b2b1549Clo
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这个基因编码一种类似于枯草杆菌蛋白酶的蛋白转化酶，它介导穿过分泌途径的各种前蛋白底物的翻译后内蛋白水解加工。编码的蛋白质是一种无活性的酶原，在内质网和高尔基体网络中经历自蛋白水解加工，生成活性酶。缺乏编码的蛋白质的小鼠在胚胎早期死亡。在胚外组织而非胚层中条件性失活此基因可避免胚胎致死性，但导致出生时死亡。可变剪接产生多种转录变异体，编码不同的异构体。[由RefSeq，2015年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Pcsk5 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
