Log In|Sign Up
中文人类
DUSP7 - Dual Specificity Phosphatase 7
Alias:
MKPX
PYST2
Favorite
双特异性磷酸酶（DUSPs）是I型基于半胱氨酸的蛋白质酪氨酸磷酸酶超家族中的一大异质子群。DUSPs的特点是它们能够去磷酸化酪氨酸和丝氨酸/苏氨酸残基。DUSP7属于一类被指定为MKPs的DUSPs，它们以与单个MKP蛋白不同的特异性去磷酸化MAPK（有丝分裂原激活的蛋白激酶）蛋白ERK（参见MIM 601795）、JNK（参见MIM 601158）和p38（参见MIM 600289）。MKPs含有高度保守的C端催化结构域和N端的Cdc25（参见MIM 116947）样（CH2）结构域。MAPK激活级联调节各种生理过程，包括细胞增殖、凋亡、分化和应激反应（Patterson等，2009年[PubMed 19228121]总结）。[由OMIM于2009年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DUSP7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
