Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
DUSP2 - Dual Specificity Phosphatase 2
Alias:
PAC1
PAC-1
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是双特异性蛋白磷酸酶亚家族的一员。这些磷酸酶通过去除磷酸丝氨酸/苏氨酸和磷酸酪氨酸残基来抑制其靶定激酶。它们负调节有丝分裂激活蛋白(MAP)激酶超家族(MAPK/ERK、SAPK/JNK、p38)的成员,这些成员与细胞增殖和分化有关。双特异性磷酸酶家族的不同成员显示出对各种MAP激酶的不同的底物特异性、不同的组织分布和亚细胞定位,以及它们表达的外部刺激的不同诱导模式。这个基因产物抑制ERK1和ERK2,主要在小造血组织中表达,并定位在核内。[由RefSeq,2008年7月提供]
Related ID:
NCBI:1844
ENSEMBL:ENSG00000158050
HGNC:3068
UNIPROT:Q05923
OMIM:603068
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1844
2
4
2272 bp
34.40
18
--
4
6
DUSP2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top