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中文人类
DUSP1 - Dual Specificity Phosphatase 1
Alias:
HVH1
MKP1
CL100
MKP-1
PTPN10
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这个基因编码的蛋白质是一种具有酪氨酸和苏氨酸双重特性的磷酸酶。编码的蛋白质可以脱磷酸化MAP激酶MAPK1/ERK2，这导致其涉及几个细胞过程。这个蛋白质似乎在人类对环境压力的细胞反应以及细胞增殖的负调控中扮演重要角色。最后，编码的蛋白质可以使一些实体瘤对化学治疗和放射治疗产生抗性，使其成为癌症治疗的目标。[由RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DUSP1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
