小鼠

Sigmar1 - sigma non-opioid intracellular receptor 1

Alias:
Oprs1
Sig1R
sigma1R
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个位于内质网的跨膜蛋白。编码的蛋白质是一个结合几种内源性配体的受体,包括N,N-二甲基色胺、孕激素和孕烯醇酮以及各种非阿片类药物。该编码蛋白质在调节离子通道活性中发挥作用,作为分子伴侣并保护细胞免受氧化应激。在人类中,这个受体与阿尔茨海默病和帕金森病、中风以及诸如抑郁症、疼痛和成瘾等多种疾病状况有关。可选剪接导致多个转录变异体编码不同的异构体。[由RefSeq,2013年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
8
4
2867 bp
25.25
8
17

Sigmar1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top