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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Nr4a2 - nuclear receptor subfamily 4, group A, member 2
Alias:
NOT
HZF-3
Nurr1
RNR-1
TINOR
TINUR
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合转录激活子活性,特异性RNA聚合酶II;糖皮质激素受体结合活性;和蛋白质异二聚化活性。参与多个过程,包括对促皮质素释放激素刺激的细胞反应;多巴胺能神经元分化;和脂肪细胞分化。在几个过程的上游或内部发挥作用,包括多巴胺生物合成过程;神经系统发育;和对安非他命的反应。位于细胞核中。在几个结构中表达,包括消化系统;耳;生殖泌尿系统;皮肤和神经系统。用于研究帕金森氏病和精神分裂症。该基因的人类同源物与帕金森氏病有关。与人类NR4A2(核受体亚家族4A成员2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:18227
ENSEMBL:ENSMUSG00000026826
UNIPROT:Q06219
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
18227
6
8
17174 bp
66.59
9
11
Nr4a2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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Protein
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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