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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ntrk2 - neurotrophic tyrosine kinase, receptor, type 2
Alias:
Tkrb
trkB
trk-B
GP145-TrkB/GP95-TrkB
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活脑源性神经营养因子结合活性及脑源性神经营养因子激活的受体活性。参与多个过程,包括脑源性神经营养因子受体信号通路;神经系统发育;以及跨突触信号传导,调节突触传递。在多个过程的上游或内部发挥作用,包括神经发生;神经元动作电位传播;以及肽酰-丝氨酸磷酸化的正向调节。位于几个细胞组分中,包括早期内质网;突触后密度;和突触后膜。在几个结构中表达,包括消化系统;心血管系统;未来大脑;生殖泌尿系统;和神经系统。该基因的人类同源物与阿尔茨海默病;自闭症;发育性癫痫性脑病58;重度抑郁症;和病理性肥胖有关。与人类NTRK2(神经营养受体酪氨酸激酶2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:18212
ENSEMBL:ENSMUSG00000055254
UNIPROT:P15209
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
18212
10
18
327499 bp
92.13
27
31
Ntrk2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
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* This data comes from NCBI.
Gene Expression
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Name
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