小鼠

Ntan1 - N-terminal Asn amidase

Alias:
PNAA
PNAD
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质通过N端规则途径参与分步蛋白质降解过程。这个蛋白质作为三级去稳定酶,将蛋白质上的N端L-天冬酰胺残基脱氨化为N端L-天冬氨酸。L-天冬氨酸底物随后与L-精氨酸结合,被特定的E3泛素连接酶识别并靶向蛋白酶体。这个基因敲除的小鼠是存活的、能繁殖的且外观正常的,但与野生型对照组相比,它们在自发活动和空间记忆方面表现出障碍。可变剪接导致多个转录变异体。[由RefSeq,2016年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
14
10
16686 bp
34.59
3
10

Ntan1 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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