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中文小鼠
Nrtn - neurturin
Alias:
NTN
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这个基因编码一种分泌性的TGF-beta(转化生长因子-β)超家族蛋白质的配体。编码的前原蛋白在蛋白水解过程中被加工成成熟蛋白。这种蛋白通过RET受体酪氨酸激酶和一个GPI连接的核心受体传递信号，并促进神经元群体的生存。这个基因的纯合子敲除小鼠在视网膜和肠道神经系统的发育中表现出缺陷，以及心脏和泪腺腺体的胆碱能神经支配减少。[RefSeq,2016年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Nrtn Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
