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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DRD4 - Dopamine Receptor D4
Alias:
D4DR
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码多巴胺受体的D4亚型。D4亚型是一种G蛋白偶联受体,可以抑制腺苷酸环化酶。它是治疗精神分裂症和帕金森病的药物靶点。这个基因的突变与各种行为表型有关,包括自主神经系统功能障碍、注意力缺陷/多动障碍和寻求新事物的个性特征。这个基因包含一个可变数量的(2-10个拷贝)串联的48个核苷酸重复序列;所示的序列包含四个重复。[由RefSeq,2008年7月提供]
Related ID:
NCBI:1815
ENSEMBL:ENSG00000069696
HGNC:3025
UNIPROT:P21917
OMIM:126452
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1815
1
4
3438 bp
43.90
87
2
5
19
DRD4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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