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中文人类
DPYD - Dihydropyrimidine Dehydrogenase
Alias:
DHP
DPD
DYPD
DHPDHASE
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这个基因编码的蛋白质是一种嘧啶分解酶，是尿嘧啶和胸腺嘧啶分解途径中的初始和限速因素。这个基因的突变导致二氢嘧啶脱氢酶缺乏，这是一种与胸腺嘧啶-尿嘧啶尿症相关的嘧啶代谢错误，并且增加接受5-氟尿嘧啶化疗的癌症病人中毒的风险。已经发现这个基因有两个转录变异体，编码不同的异构体。[由RefSeq提供，2009年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DPYD Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
