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中文人类
DPP4 - Dipeptidyl Peptidase 4
Alias:
CD26
ADABP
ADCP2
DPPIV
TP103
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DPP4基因编码二肽肽酶4，它与腺苷脱氨酶复合蛋白-2和T细胞激活抗原CD26相同。它是一种内在型II跨膜糖蛋白，也是一种丝氨酸外肽酶，可以从多肽的N端切割X-脯氨酸二肽。二肽肽酶4在葡萄糖、胰岛素代谢以及免疫调节中起着重要作用。该蛋白被证明是中东呼吸综合症冠状病毒（MERS-CoV）的功能受体，并且蛋白质建模表明，它可能在与导致COVID-19的病毒SARS-CoV-2中发挥类似的作用。[由RefSeq，2020年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DPP4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
