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中文小鼠
Nfkbib - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
Alias:
IkB
IkBb
ikB-B
IKB-beta
IKappaBbeta
NF-kappa-BIB
I-kappa-B-beta
I(Kappa)B(beta)
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这个基因编码一种核因子kappa轻链激活子B细胞增强子（NF-kappaB）的抑制剂。编码的蛋白质通过将其捕获在细胞质中，防止其通过NF-kappaB介导的转录激活。在诱导NF-kappaB的信号传导中，如细胞因子和生长因子，编码的蛋白质经历磷酸化，触发其快速的泛素化和蛋白酶体降解。选择性剪接导致多个转录变异体。[RefSeq, 2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Nfkbib Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
