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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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小鼠
Ncoa1 - nuclear receptor coactivator 1
Alias:
SRC1
NRC-1
SRC-1
SRC-a
KAT13A
NCoA-1
mNRC-1
bHLHe74
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有DNA结合活性;染色质结合活性;以及转录共激活活性。参与几个过程,包括组蛋白H4乙酰化;由半乳糖正调控从RNA聚合酶II启动子转录;以及调控细胞对药物的反应。在几个过程的上游或内部发挥作用,包括细胞对甲状腺球蛋白三碘甲状腺原氨酸的反应;迷宫层形态发生;以及调控甲状腺激素介导的信号通路。预测位于几个细胞组件中,包括染色质;胞质;核质。预测是含蛋白质复合物的一部分。预测在细胞核中活跃。在几个结构中表达,包括消化系统;大脑;早期概念期;眼睛;和生殖泌尿系统。用于研究肥胖和甲状腺激素抵抗综合症。与人类的NCOA1(核受体共激活子1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:17977
ENSEMBL:ENSMUSG00000020647
UNIPROT:P70365
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17977
19
23
272091 bp
157.02
11
15
Ncoa1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
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