人类

DNTT - DNA Nucleotidylexotransferase

Alias:
TDT
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是DNA聚合酶类型-X家族的成员,编码一个独立于模板的DNA聚合酶,催化脱氧核苷酸添加到寡核苷酸引物的3'-羟基末端。在活体内,编码的蛋白质在正常和恶性前B和前T淋巴细胞在早期分化过程中表达受到限制,在那里它通过在重排的Ig重链和T细胞受体基因片段连接处合成非种系元素(N-区域)来产生抗原受体多样性。可变剪接转录变异体编码这个基因的不同异构体已经被描述。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
11
34131 bp
58.54
24
--
10
12

DNTT Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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