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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DNTT - DNA Nucleotidylexotransferase
Alias:
TDT
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是DNA聚合酶类型-X家族的成员,编码一个独立于模板的DNA聚合酶,催化脱氧核苷酸添加到寡核苷酸引物的3'-羟基末端。在活体内,编码的蛋白质在正常和恶性前B和前T淋巴细胞在早期分化过程中表达受到限制,在那里它通过在重排的Ig重链和T细胞受体基因片段连接处合成非种系元素(N-区域)来产生抗原受体多样性。可变剪接转录变异体编码这个基因的不同异构体已经被描述。[由RefSeq,2008年7月提供]
Related ID:
NCBI:1791
ENSEMBL:ENSG00000107447
HGNC:2983
UNIPROT:P04053
OMIM:187410
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1791
2
11
34131 bp
58.54
24
--
10
12
DNTT Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
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Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
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