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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Myc - myelocytomatosis oncogene
Alias:
Myc2
Nird
Niard
bHLHe39
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一种具有多种功能的核磷酸蛋白,参与细胞周期进展、凋亡和细胞转化。它作为转录因子,调节特定目标基因的转录。这个基因的突变、过度表达、重排和易位与各种造血肿瘤、白血病和淋巴瘤有关,包括人类的Burkitt淋巴瘤。有证据表明,人类和小鼠中上游框架内的非AUG(CUG)和下游AUG起始位点的可选翻译起始导致产生具有不同N端的两个人工变异体。在压力条件下,如高细胞密度和甲硫氨酸缺乏,非AUG起始的蛋白质合成特异性且显著增加,表明其在逆境中的重要性。可选剪接产生多种转录变异体。[RefSeq,2010年4月提供]
Related ID:
NCBI:17869
ENSEMBL:ENSMUSG00000022346
UNIPROT:P01108
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17869
4
3
5021 bp
50.68
27
17
Myc Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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