小鼠

Myc - myelocytomatosis oncogene

Alias:
Myc2
Nird
Niard
bHLHe39
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一种具有多种功能的核磷酸蛋白,参与细胞周期进展、凋亡和细胞转化。它作为转录因子,调节特定目标基因的转录。这个基因的突变、过度表达、重排和易位与各种造血肿瘤、白血病和淋巴瘤有关,包括人类的Burkitt淋巴瘤。有证据表明,人类和小鼠中上游框架内的非AUG(CUG)和下游AUG起始位点的可选翻译起始导致产生具有不同N端的两个人工变异体。在压力条件下,如高细胞密度和甲硫氨酸缺乏,非AUG起始的蛋白质合成特异性且显著增加,表明其在逆境中的重要性。可选剪接产生多种转录变异体。[RefSeq,2010年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
3
5021 bp
50.68
27
17

Myc Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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