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中文小鼠
Mvk - mevalonate kinase
Alias:
MK
2310010A05Rik
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这个基因编码甲羟戊酸激酶，这是一种涉及胆固醇和非甾类异戊二烯生物合成的关键酶。编码的蛋白质完全缺失会导致小鼠胚胎致死。缺乏这个基因一个等位基因的小鼠，其脾、心、肾中甲羟戊酸的水平升高，同时血清免疫球蛋白A和D的水平也升高。可变剪接导致多个转录子变异体，编码不同的异构体。[RefSeq, 2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Mvk Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
