Predicted to enable endopeptidase inhibitor activity and protease binding activity. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in otitis media. Orthologous to human PZP (PZP alpha-2-macroglobulin like) and A2ML1 (alpha-2-macroglobulin like 1). [provided by Alliance of Genome Resources, Apr 2022]