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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Msh6 - mutS homolog 6
Alias:
GTBP
Gtmbp
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因具有以下功能: 1. 结合染色质活性 2. 结合受损的DNA 3. 结合鸟嘌呤/胸腺嘧啶错配 4. 影响多个过程,包括决定成年寿命、DNA损伤引起的内在凋亡信号通路和免疫球蛋白的体细胞多样性 5. 位于染色质中,是MutSalpha复合物的一部分 6. 在多个组织中表达,包括大脑、早期胚胎、肝脏、肺和卵母细胞 7. 人类同源基因与林奇综合症、结直肠癌、子宫内膜癌、遗传性非息肉结肠癌5型和错配修复癌症综合症有关 8. 与人类的MSH6(mutS同源物6)同源 请注意,这个基因与多种癌症有关,包括林奇综合症、结直肠癌、子宫内膜癌、遗传性非息肉结肠癌5型和错配修复癌症综合症。
Related ID:
NCBI:17688
ENSEMBL:ENSMUSG00000005370
UNIPROT:P54276
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17688
1
10
15843 bp
151.08
6
5
Msh6 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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