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Msh2 - mutS homolog 2

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有ATP水解活性和DNA结合活性。参与鸟嘌呤/胸腺嘧啶错配结合活性。参与IgA同型转换的正调控和IgG同型转换的正调控。位于DNA代谢过程、免疫系统发育和细胞内信号传导的上游或内部。位于细胞核中。是MutSalpha复合物的一部分。在几个结构中表达,包括生殖系统、心脏、肝脏、肺和尾背根神经节。用于研究林奇综合症。该基因的人类同源物涉及几种疾病,包括林奇综合症(多种)、胃肠道系统癌症(多种)、肺癌(多种)、错配修复癌症综合症和过渡细胞癌。与人类MSH2(mutS同源物2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
16
51182 bp
104.15
15
10

Msh2 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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