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中文小鼠
Mre11a - MRE11A homolog A, double strand break repair nuclease
Alias:
Mre11
Mre11b
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具有相同的蛋白质结合活性；核酸酶活性；和蛋白质C端结合活性。预测对DNA结合活性和DNA解旋酶活性有贡献。在几个过程的上游或内部发挥作用，包括双链断裂修复；减数分裂中同源染色体配对；和有丝分裂DNA损伤检查点信号。位于PML体中。与染色体，端粒区域共定位。该基因的人类同源物与乳腺癌；子宫内膜癌；胃癌；和膀胱癌有关。与人类MRE11（MRE11同源物，双链断裂修复核酸酶）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Mre11a Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
