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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DLX4 - Distal-less Homeobox 4
Alias:
BP1
DLX7
DLX8
DLX9
OFC15
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
许多含有脊椎动物同源盒的基因已经根据它们与果蝇发育基因的序列相似性被鉴定出来。Dlx基因家族的成员包含一个与Distal-less(Dll)基因同源的同源盒,Dll基因在发育中的果蝇头部和肢体表达。Distal-less(Dlx)基因家族包括至少6个不同的成员,DLX1-DLX6。DLX蛋白被认为在大脑和颅面发育中起作用。已经描述了此基因的三种转录变异体,但是其中一种变异体的完整长度尚未描述。对两种剪接变异体的研究表明,一种编码的异构体作为β-珠蛋白基因的抑制子,而另一种异构体没有这种功能。[由RefSeq,2008年7月提供]
Related ID:
NCBI:1748
ENSEMBL:ENSG00000108813
HGNC:2917
UNIPROT:Q92988
OMIM:601911
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1748
3
3
6388 bp
26.26
24
2
3
8
DLX4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Acting
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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