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中文人类
AFP - Alpha Fetoprotein
Alias:
AFPD
FETA
HPAFP
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这个基因编码甲胎蛋白，这是一种主要血浆蛋白，在胎儿期由卵黄囊和肝脏产生。成年人体内甲胎蛋白的表达通常与肝癌和畸胎瘤有关，并对晚期胃癌的治疗具有预后价值。然而，遗传性甲胎蛋白持续存在于无明显病理症状的个人中也可能被发现。该蛋白质被认为是血清白蛋白的胎儿对应物，甲胎蛋白和白蛋白基因在染色体4上以相同的转录方向成对存在。甲胎蛋白以单体、二聚体和三聚体的形式存在，并结合铜、镍、脂肪酸和胆红素。羊水中甲胎蛋白的水平用于测量肾脏蛋白质损失以筛查脊柱裂和无脑畸形。[由RefSeq，2019年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
AFP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
