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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mmp9 - matrix metallopeptidase 9
Alias:
Clg4b
Gel B
MMP-9
B/MMP9
pro-MMP-9
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于基质金属蛋白酶家族的成员,该家族是参与组织重塑、伤口修复、动脉粥样硬化进展和肿瘤侵袭的细胞外基质降解酶。编码的前原蛋白经历蛋白水解处理,生成成熟的、锌依赖的内肽酶,该酶降解IV、V和XI型的胶原蛋白和弹性蛋白。缺乏编码蛋白的小鼠表现出骨骼生长板血管化和骨化异常模式,所有肿瘤阶段的角质细胞过度增殖减少,侵袭性肿瘤发生率降低,并对实验性自身免疫性脑脊髓炎具有抵抗力。[RefSeq,2016年2月提供]
Related ID:
NCBI:17395
ENSEMBL:ENSMUSG00000017737
UNIPROT:P41245
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17395
2
13
15525 bp
80.53
11
12
Mmp9 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Interactions
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Type
Name
MGI
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References Literature
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