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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mmp8 - matrix metallopeptidase 8
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码金属蛋白酶家族的一员,该家族参与组织重塑、伤口修复、动脉粥样硬化进展和肿瘤侵袭。编码的前原蛋白经历蛋白水解处理,生成成熟的、锌依赖的内肽酶,该酶降解I、II和III型胶原蛋白。缺乏编码蛋白的小鼠在各种试剂中表现出炎症反应异常。这个基因位于染色体9上其他金属蛋白酶基因簇中。[RefSeq,2016年2月提供]
Related ID:
NCBI:17394
ENSEMBL:ENSMUSG00000005800
UNIPROT:O70138
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17394
1
10
10058 bp
53.13
6
4
Mmp8 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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