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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mmp2 - matrix metallopeptidase 2
Alias:
GelA
Clg4a
MMP-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于基质金属蛋白酶家族的成员,该家族是参与组织重塑、伤口修复、动脉粥样硬化进展和肿瘤侵袭的细胞外基质降解酶。编码的前原蛋白经历蛋白水解处理,生成成熟的、锌依赖的内肽酶,该酶水解胶原蛋白、明胶、层粘连蛋白、纤维连接蛋白和弹性蛋白。缺乏编码蛋白的小鼠表现出血管生成受到抑制,以及具有关节炎特征的多中心骨质疏松症状减弱,包括骨骼和颅面发育异常。[RefSeq,2016年2月提供]
Related ID:
NCBI:17390
ENSEMBL:ENSMUSG00000031740
UNIPROT:P33434
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17390
2
13
26130 bp
74.10
5
11
Mmp2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
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Interactions
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Acting
Regulation
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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