小鼠

Mmp13 - matrix metallopeptidase 13

Alias:
Clg
Mmp1
MMP-13
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码基质金属蛋白酶家族的一员,在伤口愈合、骨骼发育和骨重塑中发挥作用。编码的蛋白质通过移除N-端激活肽而被激活,生成一个依赖锌的内肽酶,可以切割各种天然的胶原蛋白,包括I型-IV型、X型和XIV型。缺乏编码的蛋白质的小鼠在生长板软骨中表现出严重的缺陷,以及软骨内骨发育的延迟。缺乏编码的蛋白质还会损伤伤口愈合过程,因为伤口部位的角质细胞迁移和血管密度减少。这个基因位于染色体9上的其他基质金属蛋白酶基因簇中。[RefSeq,2015年6月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
10
10820 bp
54.18
9
14

Mmp13 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

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Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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