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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mmp11 - matrix metallopeptidase 11
Alias:
ST3
SL-3
Stmy3
MMP-11
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个矩阵金属蛋白酶家族的成员,该家族参与例如胚胎发育和肿瘤进展过程中的细胞外基质重塑。编码的蛋白质在翻译后通过furin内肽酶进行蛋白水解加工,形成活性酶。将表达编码蛋白质的细胞皮下引入裸鼠中会导致肿瘤发病率增加。缺乏编码的蛋白质的小鼠表现出化学诱导肿瘤发病率降低。可选的剪接导致多个转录变异体。[由RefSeq,2015年4月提供]
Related ID:
NCBI:17385
ENSEMBL:ENSMUSG00000000901
UNIPROT:Q02853
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17385
2
8
9281 bp
55.44
6
8
Mmp11 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
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Interactions
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Acting
Regulation
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Type
Name
MGI
Strain of Origin
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References Literature
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