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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mmp12 - matrix metallopeptidase 12
Alias:
MME
Mmel
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码金属蛋白酶家族的一员,该家族参与细胞外基质的降解,组织重塑,伤口修复,动脉粥样硬化的发展和肿瘤侵袭。编码的前原蛋白经历蛋白水解过程,生成成熟的,锌依赖的内肽酶。缺乏编码蛋白的小鼠降解细胞外基质成分的能力减弱,对长期吸烟暴露没有发展肺气肿,并且在细菌感染后清除受损和死亡率增加。这个基因位于染色体9上的其他金属蛋白酶基因簇中。交替剪接产生多个转录变异体,编码不同的异构体。[RefSeq,2016年2月提供]
Related ID:
NCBI:17381
ENSEMBL:ENSMUSG00000049723
UNIPROT:P34960
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17381
4
10
16065 bp
54.97
6
10
Mmp12 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
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Interactions
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Acting
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Type
Name
MGI
Strain of Origin
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No data available
References Literature
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Year
IF
No Data Found!
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