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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mme - membrane metallo endopeptidase
Alias:
NEP
SFE
CD10
CALLA
6030454K05Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有肽酶活性。参与淀粉样蛋白-β清除;长期突触增强的正调控;以及疼痛的感知。在淀粉样蛋白-β代谢过程的上游或内部发挥作用。位于几个细胞组件中,包括树突;神经元突起终端;和突触囊泡。在几个结构中表达,包括消化系统;中枢神经系统;生殖泌尿系统;肝和胆系统;和乳腺。用于研究阿尔茨海默病。该基因的人类同源物与阿尔茨海默病;Charcot-Marie-Tooth病轴突型2T;小脑共济失调43型;脑淀粉样血管病;和膜性肾小球肾炎有关。与人MME(膜金属肽酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:17380
ENSEMBL:ENSMUSG00000027820
UNIPROT:Q61391
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17380
5
23
88503 bp
85.70
6
7
Mme Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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