小鼠

Mme - membrane metallo endopeptidase

Alias:
NEP
SFE
CD10
CALLA
6030454K05Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有肽酶活性。参与淀粉样蛋白-β清除;长期突触增强的正调控;以及疼痛的感知。在淀粉样蛋白-β代谢过程的上游或内部发挥作用。位于几个细胞组件中,包括树突;神经元突起终端;和突触囊泡。在几个结构中表达,包括消化系统;中枢神经系统;生殖泌尿系统;肝和胆系统;和乳腺。用于研究阿尔茨海默病。该基因的人类同源物与阿尔茨海默病;Charcot-Marie-Tooth病轴突型2T;小脑共济失调43型;脑淀粉样血管病;和膜性肾小球肾炎有关。与人MME(膜金属肽酶)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
23
88503 bp
85.70
6
7

Mme Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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