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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mgp - matrix Gla protein
Alias:
Mglap
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码成骨蛋白/基质Gla家族蛋白质的一员。编码的维生素K依赖性蛋白由软骨细胞和血管平滑肌细胞分泌,并作为异位组织钙化的生理抑制剂发挥作用。这种蛋白还抑制血管生成。缺乏这个基因功能拷贝的小鼠内皮细胞分化受损,体型减小,血管钙化并破裂,导致过早死亡。[RefSeq,2016年9月提供]
Related ID:
NCBI:17313
ENSEMBL:ENSMUSG00000030218
UNIPROT:P19788
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17313
1
4
3389 bp
12.36
8
4
Mgp Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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