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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Abcc1 - ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Alias:
MRP
Mrp1
Mdrap
Abcc1a
Abcc1b
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的膜关联蛋白是ATP结合盒(ABC)转运子超家族的一员。ABC蛋白在细胞内外膜之间运输各种分子。ABC基因分为七个不同的亚家族(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White)。这个完整的转运子是MRP亚家族的一员,与多药抗性有关。这个蛋白在对抗有毒化合物中起到关键作用,并作为白细胞三烯C4的主要高亲和力转运体。编码的蛋白还可能作为类固醇激素及其代谢物的转运体在类固醇激素内稳态中起到关键作用。[由RefSeq,2011年11月提供]
Related ID:
NCBI:17250
ENSEMBL:ENSMUSG00000023088
UNIPROT:O35379
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
17250
4
31
113427 bp
171.19
6
9
Abcc1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
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Abundance
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Interactions
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Acting
Regulation
Detail
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Score
No data available
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Type
Name
MGI
Strain of Origin
Publications
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No data available
References Literature
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Year
IF
No Data Found!
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