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中文小鼠
Cma1 - chymase 1, mast cell
Alias:
Mcp5
Mcp-5
Mcpt5
MMCP-5
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这个基因编码一种丝氨酸蛋白酶，属于肽酶家族S1。它在肥大细胞中表达，被认为在细胞外基质的降解、黏膜下腺分泌的调节和血管活性肽的生成中发挥作用。编码的前原原蛋白经历蛋白水解加工，生成具有弹性酶样活性的功能性酶。缺乏编码蛋白的小鼠表现出骨骼肌缺血-再灌注损伤显著减轻。这个基因位于染色体14上一个相关肥大细胞蛋白酶基因簇中。[RefSeq, Nov 2015提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Cma1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
