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中文小鼠
Mcl1 - myeloid cell leukemia sequence 1
Alias:
Mcl-1
Gm52627
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激活BH3结构域结合活性。参与无配体时的外在凋亡信号通路；负调控凋亡过程；并正调控氧化应激诱导的神经元内在凋亡信号通路。位于DNA损伤响应的凋亡线粒体变化和内在凋亡信号通路上游。位于几个细胞组件中，包括胞质；线粒体基质；和核仁。在几个结构中表达，包括消化系统；胚泡；大脑；生殖泌尿系统；和血淋巴样系统腺体。与人类MCL1（MCL1凋亡调节剂，BCL2家族成员）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Mcl1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
